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While native GHRH has an extremely short biological half-life—rapidly degraded by ubiquitous circulating enzymes like dipeptidyl peptidase-4 (DPP-4)—tesamorelin has been bioengineered for enzymatic resistance and prolonged activity

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Following granule exocytosis, perforin facilitates the delivery of granzymes into the cytosol of the target cell where they cleave numerous substrates, including caspases, resulting in the rapid induction of apoptosis 7,8

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